MITOFERRIN2 IS A SYNTHETIC LETHAL TARGET FOR CHROMOSOME 8P DELETED CANCERS




Principles of agonist recognition in Cys-loop receptors

Cys-loop receptors are ligand-gated ion channels that are activated by a structurally diverse array of neurotransmitters, including acetylcholine, serotonin, glycine and GABA.After the term chemoreceptor emerged over 100 years ago, there was some wait until affinity labeling, molecular cloning, functional studies and X-ray crystallography experimen

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